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Mouse Frk Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB3184
产品名称
Mouse Frk Rabbit Polyclonal Antibody (C-term)
别名
Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, Frk, Bsk, Iyk
类别
常规抗体
推荐应用
WB
反应种属
Human, Rat, Mouse
Human Swissprot No.
Q922K9
特异性
This Mouse Frk antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 476-509 amino acids from the C-terminal region of mouse Frk.
稀释度
WB~~1:1000
预测分子量
59kDa
同种型
Rabbit Ig
背景介绍
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
组织表达
Expressed in intestinal tract, fetal and adult islets of Langerhans, kidney, liver and lung
细胞定位
Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.
期货
现货

Western blot analysis of lysate from mouse lung tissue lysate, using Frk Antibody (C-term). BD-PB3184 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

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