BD-PB3175-(Mouse) Suz12 Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

(Mouse) Suz12 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB3175

产品名称

(Mouse) Suz12 Rabbit Polyclonal Antibody (Center)

别名

Polycomb protein Suz12, Suppressor of zeste 12 protein homolog, Suz12, D11Ertd530e, Kiaa0160

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Swissprot No.

Q80U70

特异性

This Mouse Suz12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 496-530 amino acids from the Central region of Mouse Suz12.

稀释度

WB~~1:1000

预测分子量

83kDa

同种型

Rabbit Ig

背景介绍

Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity). Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8.

组织表达

Expressed in embryonic stem cells.

细胞定位

Nucleus. Chromosome. Note=Localizes to the inactive X chromosome in trophoblast stem cells

期货

现货

Western blot analysis of lysate from mouse F9 cell line, using Suz12 Antibody (Center). BD-PB3175 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.