BD-PB3172

Mouse Nkx2-5 Rabbit Polyclonal Antibody (Center)

Homeobox protein Nkx-25, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E, Nkx2-5, Csx, Nkx-25, Nkx2e

常规抗体

WB

Human, Rat, Mouse

P42582

This mouse Nkx2-5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 192-235 amino acids from the Central region of mouse Nkx2-5.

WB~~1:1000

34kDa

Rabbit Ig

Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.

Predominantly in the adult and embryonic heart, and to a lesser extent in lingual muscle, spleen and stomach

Nucleus.

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