BD-PB3167-Mouse Pax6 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

Mouse Pax6 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB3167

产品名称

Mouse Pax6 Rabbit Polyclonal Antibody (C-term)

别名

Paired box protein Pax-6, Oculorhombin, Pax6, Pax-6, Sey

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Swissprot No.

P63015

特异性

This Mouse Pax6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 404-436 amino acids from the C-terminal region of Mouse Pax6.

稀释度

WB~~1:1000

预测分子量

47kDa

同种型

Rabbit Ig

背景介绍

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).

组织表达

Expressed in osteoclasts. [Isoform 3]: Dominant isoform expressed in the eye, including in the retina and cornea (PubMed:21084637). Weakly expressed in the lens epithelium (PubMed:21084637)

细胞定位

Nucleus. [Isoform 3]: Nucleus. Cytoplasm

期货

现货

Western blot analysis of lysate from mouse cerebellum tissue lysate, using Pax6 Antibody (C-term). BD-PB3167 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.