产品名称
AQP8 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O94778
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O94778/entry
Mouse Swissprot No.
P56404
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P56404
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P56405
免疫原
Synthesized peptide derived from human protein . at AA range: 70-150
特异性
AQP8 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. [provided by RefSeq, Jul 2008],
组织表达
Detected in the sperm midpiece (at protein level) (PubMed:28042826). Expressed only in pancreas and colon.
细胞定位
Mitochondrion membrane ; Multi-pass membrane protein .
功能
domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Expressed only in pancreas and colon.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
