产品名称
AQP6 Rabbit Polyclonal Antibody
蛋白名称
Aquaporin-6 (AQP-6) (Aquaporin-2-like) (Kidney-specific aquaporin) (hKID)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q13520
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q13520/entry
Mouse Swissprot No.
Q8C4A0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C4A0
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9WTY0
免疫原
Synthesized peptide derived from human protein . at AA range: 60-140
特异性
AQP6 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic vesicle membrane ; Multi-pass membrane protein .
功能
domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
