BD-PB3096

Mouse Myocd Rabbit Polyclonal Antibody (C-term)

Myocardin, Basic SAP coiled-coil transcription activator 2, SRF cofactor protein, Myocd, Bsac2, Mycd, Srfcp

常规抗体

WB

Human, Rat, Mouse

Q8VIM5

This Mouse Myocd antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 743-777 amino acids from the C-terminal region of Mouse Myocd.

WB~~1:1000

101kDa

Rabbit Ig

Smooth muscle cells (SM) and cardiac muscle cells- specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis). Isoform 1 mediates the cardiac transcription factor MEF2C-dependent transcription. Isoform 1 and isoform 3 are more active than isoform 2 and isoform 4 in stimulating cardiac muscle promoters.

Expressed in heart, aorta, and in smooth muscle cell-containing tissues: stomach, bladder and uterus. Isoform 1 and isoform 3 are predominantly expressed in cardiac muscle whereas isoform 4 and isoform 5 are predominantly expressed in SMC-rich tissues Isoform 3 is the most abundant isoform in the heart from embryo to adult.

Nucleus speckle. Note=Nuclear, with a punctate intranuclear pattern with exclusion from nuclei

现货