BD-PB3092-PAX6 Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

PAX6 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB3092

产品名称

PAX6 Rabbit Polyclonal Antibody (Center)

别名

Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Swissprot No.

P26367

特异性

This PAX6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-214 amino acids from the Central region of human PAX6.

稀释度

WB~~1:1000

预测分子量

47kDa

同种型

Rabbit Ig

背景介绍

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

组织表达

[Isoform 1]: Expressed in lymphoblasts.

细胞定位

Nucleus {ECO:0000250|UniProtKB:P63015}. [Isoform 5a]: Nucleus {ECO:0000250|UniProtKB:P63016}

期货

现货

Western blot analysis of lysate from HepG2 cell line, using PAX6 Antibody (Center). BD-PB3092 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.