产品名称
B2L14 Rabbit Polyclonal Antibody
蛋白名称
Apoptosis facilitator Bcl-2-like protein 14 (Bcl2-L-14) (Apoptosis regulator Bcl-G)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9BZR8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BZR8/entry
Mouse Swissprot No.
Q9CPT0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CPT0
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q6AYK4
免疫原
Synthesized peptide derived from human protein . at AA range: 200-280
特异性
B2L14 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009],
组织表达
Isoform 1 is widely expressed. Isoform 2 is testis-specific.
细胞定位
Cytoplasm .; [Isoform 1]: Cytoplasm, cytosol. Diffusely distributed throughout the cytosol.; [Isoform 2]: Endomembrane system. Predominantly localized to cytosolic organelles.
功能
function:May play a role in apoptosis.,similarity:Belongs to the Bcl-2 family.,subcellular location:Diffusely distributed throughout the cytosol.,subcellular location:Predominantly localized to cytosolic organelles.,tissue specificity:Isoform 1 is widely expressed and isoform 2 is testis-specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
