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ASH2L Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB3090
产品名称
ASH2L Rabbit Polyclonal Antibody (Center)
别名
Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2-like protein, ASH2L, ASH2L1
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Swissprot No.
Q9UBL3
特异性
This ASH2L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 237-270 amino acids from the Central region of human ASH2L.
稀释度
WB~~1:1000
预测分子量
69kDa
同种型
Rabbit Ig
背景介绍
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
组织表达
Ubiquitously expressed. Predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes.
细胞定位
Nucleus.
期货
现货

Western blot analysis of lysates from mouse F9, human K562 cell line (from left to right), using ASH2L Antibody (Center). BD-PB3090 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

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