BD-PB3084-(Mouse) Wdr5 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

(Mouse) Wdr5 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PB3084

产品名称

(Mouse) Wdr5 Rabbit Polyclonal Antibody

别名

WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WD repeat-containing protein BIG-3, Wdr5, Big, Big3

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Swissprot No.

P61965

特异性

This Mouse Wdr5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the region of mouse Wdr5.

稀释度

WB~~1:1000

预测分子量

37kDa

同种型

Rabbit Ig

背景介绍

Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity).

组织表达

Expressed in liver (at protein level). Detected in brain, testis and kidney.

细胞定位

Nucleus.

期货

现货

Western blot analysis of lysates from human liver tissue and mouse NIH/3T3 cell line(from left to right), using (Mouse) Wdr5 Antibody. BD-PB3084 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.