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WDR5 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB3083
产品名称
WDR5 Rabbit Polyclonal Antibody (C-term)
别名
WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WDR5, BIG3
类别
常规抗体
推荐应用
WB
反应种属
Human, Rat, Mouse
Human Swissprot No.
P61964
特异性
This WDR5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 321-354 amino acids from the C-terminal region of human WDR5.
稀释度
WB~~1:1000
预测分子量
37kDa
同种型
Rabbit Ig
背景介绍
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
细胞定位
Nucleus
期货
现货

Western blot analysis of lysates from Hela, mouse NIH/3T3 cell line (from left to right), using WDR5 Antibody (C-term)at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

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