产品名称
MOUSE Bcar3 Rabbit Polyclonal Antibody (C-term)
别名
Breast cancer anti-estrogen resistance protein 3, p130Cas-binding protein AND-34, Bcar3, And34
Human Swissprot No.
Q9QZK2
特异性
This MOUSE Bcar3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 785-818 amino acids from the C-terminal region of human MOUSE Bcar3.
背景介绍
May act as an adapter protein and couple activated growth factor receptors to signaling molecules that regulate src kinase activity and promote cell migration.
组织表达
Abundantly expressed in the lung and brain, with lower expression in splenic lymphocytes and liver (at protein level) (PubMed:19365570). Expressed in splenic lymphocytes (at protein level) (PubMed:19365570). Expressed in the lymph node cortical region, periphery of the splenic white pulp and in alveolar lung fibroblasts (PubMed:19365570). Expressed in epithelial cells in the lens equatorial region and early stage nucleated cortical lens fiber cells (PubMed:19365570). Expressed in the thymus (PubMed:10438950). Expressed in B-cells (PubMed:12517963).
细胞定位
Cytoplasm. Cell junction, focal adhesion Note=Localization to focal adhesions depends on interaction with PTPRA