BD-PB3073-PCGF6 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

PCGF6 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB3073

产品名称

PCGF6 Rabbit Polyclonal Antibody (C-term)

别名

Polycomb group RING finger protein 6, Mel18 and Bmi1-like RING finger, RING finger protein 134, PCGF6, MBLR, RNF134

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Swissprot No.

Q9BYE7

特异性

This PCGF6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 261-295 amino acids from the C-terminal region of human PCGF6.

稀释度

WB 1:1000

预测分子量

39kDa

同种型

Rabbit Ig

背景介绍

Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

组织表达

Ubiquitous.

细胞定位

Nucleus

期货

现货

Fluorescent image of Hela cells stained with PCGF6 Antibody (C-term). BD-PB3073 was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor? 555 conjugated with Phalloidin (red).

Western blot analysis of lysate from human kidney tissue, using PCGF6 Antibody (C-term). BD-PB3073 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.