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Mouse Frk Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB3033
产品名称
Mouse Frk Rabbit Polyclonal Antibody (C-term)
别名
Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, Frk, Bsk, Iyk
类别
常规抗体
推荐应用
WB
反应种属
Human, Rat, Mouse
Human Swissprot No.
Q922K9
特异性
This Mouse Frk antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 482-516 amino acids from the C-terminal region of human Mouse Frk.
稀释度
WB~~1:500-1:1000
预测分子量
59kDa
同种型
Rabbit Ig
背景介绍
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
组织表达
Expressed in intestinal tract, fetal and adult islets of Langerhans, kidney, liver and lung
细胞定位
Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.
期货
现货

Western blot analysis of lysates from K562 cell line, mouse small intestine, rat stomach tissue lysate(from left to right), using Frk Antibody (C-term). BD-PB3033 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

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