产品名称
ANGP4 Rabbit Polyclonal Antibody
蛋白名称
Angiopoietin-4 (ANG-4) (Angiopoietin-3) (ANG-3)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9Y264
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y264/entry
Mouse Swissprot No.
Q9WVH6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WVH6
免疫原
Synthesized peptide derived from human protein . at AA range: 150-230
特异性
ANGP4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008],
组织表达
Highly expressed in the lung with much lower levels found in other tissues.
功能
caution:Was originally (PubMed:10218486) called angiopoietin-3.,function:Binds to tyrosine-protein kinase receptor TIE2 and activates it.,similarity:Contains 1 fibrinogen C-terminal domain.,tissue specificity:Highly expressed in the lung with much lower levels found in other tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
