BD-PB2985-VAC14 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

VAC14 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2985

产品名称

VAC14 Rabbit Polyclonal Antibody (C-term)

别名

Protein VAC14 homolog, Tax1-binding protein 2, VAC14, TAX1BP2, TRX

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Swissprot No.

Q08AM6

特异性

This VAC14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 769-802 amino acids from the C-terminal region of human VAC14.

稀释度

WB~~1:1000

预测分子量

88kDa

同种型

Rabbit Ig

背景介绍

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.

组织表达

Ubiquitously expressed.

细胞定位

Endosome membrane. Microsome membrane {ECO:0000250|UniProtKB:Q80W92}. Note=Mainly associated with membranes of the late endocytic pathway

期货

现货

Western blot analysis of lysate from rat spleen tissue lysate, using VAC14 Antibody (C-term). BD-PB2985 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.