产品名称
(DANRE) gapdh Rabbit Polyclonal Antibody (C-term)
别名
Glyceraldehyde-3-phosphate dehydrogenase, Peptidyl-cysteine S-nitrosylase GAPDH, 2699-, gapdh {ECO:0000312|ZFIN:ZDB-GENE-030115-1}
Human Swissprot No.
Q5XJ10
特异性
This (DANRE) gapdh antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 273-298 amino acids from the C-terminal region of human (DANRE) gapdh.
背景介绍
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins (By similarity).
细胞定位
Cytoplasm, cytosol {ECO:0000250|UniProtKB:P04797}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P04797}. Nucleus {ECO:0000250|UniProtKB:P04797}
