BD-PB2904-REG3A Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

REG3A Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2904

产品名称

REG3A Rabbit Polyclonal Antibody (C-term)

别名

Regenerating islet-derived protein 3-alpha, REG-3-alpha, Hepatointestinal pancreatic protein, HIP/PAP, Human proislet peptide, Pancreatitis-associated protein 1, Regenerating islet-derived protein III-alpha, Reg III-alpha, Regenerating islet-derived protein 3-alpha 165 kDa form, Regenerating islet-derived protein 3-alpha 15 kDa form, REG3A, HIP, PAP, PAP1

类别

常规抗体

推荐应用

反应种属

Human

Human Swissprot No.

Q06141

特异性

This REG3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 129-163 amino acids from the C-terminal region of human REG3A.

稀释度

FC~~1:25;WB~~1:1000

预测分子量

19kDa

同种型

Rabbit Ig

背景介绍

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.

组织表达

Highly expressed in epidermal keratinocytes of psoriasis patients (at protein level). Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis.

细胞定位

Secreted. Note=Found in the apical region of pancreatic acinar cells

期货

现货

Flow cytometric analysis of HepG2 cells using REG3A Antibody (C-term)(green) compared to an isotype control of rabbit IgG(blue). BD-PB2904 was diluted at 1:25 dilution. An Alexa Fluor® 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.

Western blot analysis of lysate from human pancreas tissue lysate, using REG3A Antibody (C-term). BD-PB2904 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.