产品名称
CTNL1 Rabbit Polyclonal Antibody
蛋白名称
Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UBT7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UBT7/entry
Mouse Swissprot No.
O88327
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O88327
免疫原
Synthesized peptide derived from human protein . at AA range: 150-230
特异性
CTNL1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).,induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis.,similarity:Belongs to the vinculin/alpha-catenin family.,subunit:Interacts with ARHGEF1.,tissue specificity:Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.,
组织表达
Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.
细胞定位
Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein .
功能
function:May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).,induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis.,similarity:Belongs to the vinculin/alpha-catenin family.,subunit:Interacts with ARHGEF1.,tissue specificity:Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
