产品名称
M Tfap2c Rabbit Polyclonal Antibody (N-term)
别名
Transcription factor AP-2 gamma, AP2-gamma, AP-22, Activating enhancer-binding protein 2 gamma, Tfap2c, Tcfap2c
Human Swissprot No.
Q61312
Mouse Gene ID
NP_001153168.1;NP_033361.2
特异性
This Mouse Tfap2c antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-144 amino acids from the N-terminal region of Mouse Tfap2c.
背景介绍
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
组织表达
Expressed in lung, ovary and testis. Expressed in most squamous epithelia. Also, detected in several exocrine glands including the prostate, the preputial and salivary glands, serous glands of the tongue and ocular harderian glands
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.