BD-PB2852

USP22 (1Q17)Mouse Monoclonal Antibody(C-term)

Ubiquitin carboxyl-terminal hydrolase 22, Deubiquitinating enzyme 22, Ubiquitin thioesterase 22, Ubiquitin-specific-processing protease 22, USP22, KIAA1063, USP3L

常规抗体

WB

Human

NP_056091.1

Q9UPT9

Purified His-tagged USP22 protein was used to produced this monoclonal antibody.

WB~~1:500

60kDa

IgG1

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver

Nucleus {ECO:0000250|UniProtKB:Q5DU02}.

现货

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.