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BAIAP2 (8T17)Mouse Monoclonal Antibody(C-term)

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产品基本信息

产品货号
BD-PB2851
产品名称
BAIAP2 (8T17)Mouse Monoclonal Antibody(C-term)
别名
Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, FLAF3, Insulin receptor substrate p53/p58, IRS-58, IRSp53/58, Insulin receptor substrate protein of 53 kDa, IRSp53, Insulin receptor substrate p53, BAIAP2
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Gene ID
NP_001138360.1;NP_006331.1;NP_059344.1;NP_059345.1
Human Swissprot No.
Q9UQB8
特异性
Purified His-tagged BAIAP2 protein was used to produced this monoclonal antibody.
稀释度
WB~~1:1000
预测分子量
61kDa
同种型
IgG2b
背景介绍
Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.
组织表达
Isoform 1 and isoform 4 are expressed almost exclusively in brain. Isoform 4 is barely detectable in placenta, prostate and testis. A short isoform is ubiquitous, with the highest expression in liver, prostate, testis and placenta
细胞定位
Cytoplasm. Membrane; Peripheral membrane protein. Cell projection, filopodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Note=Detected throughout the cytoplasm in the absence of specific binding partners. Detected in filopodia and close to membrane ruffles. Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites
期货
现货
纯化
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

BAIAP2 Antibody (C-term)western blot analysis in K562 cell line and mouse brain tissue lysates (35μg/lane).This demonstrates the BAIAP2 antibody detected the BAIAP2 protein (arrow).

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