产品名称
GOLPH3 (1I16)Mouse Monoclonal Antibody(C-term)
别名
Golgi phosphoprotein 3, Coat protein GPP34, Mitochondrial DNA absence factor, MIDAS, GOLPH3, GPP34
Human Gene ID
NP_071413.1
Human Swissprot No.
Q9H4A6
特异性
Purified His-tagged GOLPH3 protein was used to produced this monoclonal antibody.
背景介绍
Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains. Involved in modulation of mTOR signaling. Involved in the regulation of mitochondrial lipids, leading to increase of mitochondrial mass. Potential oncogene.
组织表达
Detected in muscle fibers of patients with mitochondrial diseases; not detected in normal muscle fibers
细胞定位
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side Mitochondrion intermembrane space. Cell membrane Endosome. Note=Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes.
纯化
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
