BD-PB2825-UCH37(UCHL5)(12Y13)Mouse Monoclonal Antibody(N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

UCH37(UCHL5)(12Y13)Mouse Monoclonal Antibody(N-term)

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产品基本信息

产品货号

BD-PB2825

产品名称

UCH37(UCHL5)(12Y13)Mouse Monoclonal Antibody(N-term)

别名

Ubiquitin carboxyl-terminal hydrolase isozyme L5, UCH-L5, Ubiquitin C-terminal hydrolase UCH37, Ubiquitin thioesterase L5, UCHL5, UCH37

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001186190.1;NP_001186191.1;NP_001186192.1;NP_057068.1

Human Swissprot No.

Q9Y5K5

特异性

Purified His-tagged UCH37 protein was used to produced this monoclonal antibody.

稀释度

WB~~1:2000-1:4000

预测分子量

38kDa

同种型

IgG1

背景介绍

Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.

细胞定位

Cytoplasm. Nucleus. Note=Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus

期货

现货

纯化

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

All lanes : Anti-UCH37 (UCHL5) at 1:2000-1:4000 dilution Lane 1: 293 whole cell lysate Lane 2: NCI-H460 whole cell lysate Lane 3: HeLa whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 37 kDa Blocking/Dilution buffer: 5% NFDM/TBST.