产品名称
A1AG1 Rabbit Polyclonal Antibody
蛋白名称
Alpha-1-acid glycoprotein 1 (AGP 1) (Orosomucoid-1) (OMD 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P02763
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P02763/entry
Mouse Swissprot No.
Q60590
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q60590
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
A1AG1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008],
组织表达
Expressed by the liver and secreted in plasma.
功能
function:Appears to function in modulating the activity of the immune system during the acute-phase reaction.,induction:Synthesis is controlled by glucocorticoids, interleukin-1 and interleukin-6, It increases 5- to 50-fold upon inflammation.,polymorphism:Three common alleles of ORM1 are known. ORM1*F1 has Gln-38/Val-174; ORM1*F2 has Gln-38/Met-174 and ORM1*S has Arg-38/Val-174. The sequence shown is that of allele ORM1*F1.,similarity:Belongs to the calycin superfamily. Lipocalin family.,tissue specificity:Expressed by the liver and secreted in plasma.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
