BD-PB2778-Mouse TSC1 Rabbit Polyclonal Antibody (C-term S1138)-现货抗体产品库武汉枢密脑科学技术有限公司

Mouse TSC1 Rabbit Polyclonal Antibody (C-term S1138)

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产品基本信息

产品货号

BD-PB2778

产品名称

Mouse TSC1 Rabbit Polyclonal Antibody (C-term S1138)

别名

Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243

类别

常规抗体

推荐应用

反应种属

Mouse

Human Swissprot No.

Q9EP53

Mouse Gene ID

NP_075025.2

特异性

This Mouse TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1117-1144 amino acids from the C-terminal region of mouse TSC1.

稀释度

WB~~1:1000

预测分子量

129kDa

同种型

Rabbit Ig

背景介绍

In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

细胞定位

Cytoplasm {ECO:0000250|UniProtKB:Q92574}. Membrane {ECO:0000250|UniProtKB:Q92574}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q92574}. Note=At steady state found in association with membranes. {ECO:0000250|UniProtKB:Q92574}

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-Mouse TSC1 Antibody (S1138) at 1:1000 dilution + mouse liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 129 kDa Blocking/Dilution buffer: 5% NFDM/TBST.