产品名称
Mouse Mast1 Rabbit Polyclonal Antibody (C-term)
别名
Microtubule-associated serine/threonine-protein kinase 1, Syntrophin-associated serine/threonine-protein kinase, Mast1 {ECO:0000312|MGI:MGI:1861901}
Human Gene ID
NP_064329.2
Human Swissprot No.
Q9R1L5
特异性
This Mouse Mast1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1438-1464 amino acids from the C-terminal region of mouse Mast1.
背景介绍
Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.
组织表达
Expressed in the brain (PubMed:30449657). Expressed in the developing cortical plate, the intermediate zone and corpus callosal fibers that cross the midline (PubMed:30449657). Detected at low levels in the testis, liver and spleen (PubMed:30449657). Expressed in proximity to neuronal nuclei throughout the cortex and cerebellum, and in the vascular endothelium. Also detected in ependymal cells, the choroid plexus, and in developing spermatid acrosomes
细胞定位
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Note=Also localized in the soma of neurons (PubMed:30449657). Observed as punctate clusters in the processes of interneurons and along the cell body periphery Colocalizes with syntrophins at the cell membrane
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
