产品名称
LCE2B Rabbit Polyclonal Antibody
基因名称
LCE2B LEP10 SPRL1B XP5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/26239
Human Swissprot No.
O14633
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O14633/entry
免疫原
Synthesized peptide derived from human LCE2B AA range: 31-81
特异性
This antibody detects endogenous levels of LCE2B at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is one of the at least 20 genes expressed during epidermal differentiation and located on chromosomal band 1q21. This gene is involved in epidermal differentiation, and it is expressed at high levels in normal and psoriatic skin, but not in cultured keratinocytes or in any other tested cell types or tissues. [provided by RefSeq, Jul 2008],
组织表达
Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.
细胞定位
cornified envelope,cytoplasm,
功能
function:Precursors of the cornified envelope of the stratum corneum.,induction:By calcium and UVB.,miscellaneous:Belongs to the LCE cluster present on 1q21.,similarity:Belongs to the LCE family.,tissue specificity:Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.