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SPR Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB2750
产品名称
SPR Rabbit Polyclonal Antibody (C-term)
别名
Sepiapterin reductase, SPR, SPR
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Gene ID
NP_003115.1
Human Swissprot No.
P35270
特异性
This SPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the C-terminal region of human SPR.
稀释度
WB~~1:1000
预测分子量
28kDa
同种型
Rabbit Ig
背景介绍
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
细胞定位
Cytoplasm.
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-SPR Antibody (C-term) at 1:1000 dilution + A549 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of SPR Antibody (C-term) in mouse liver tissue lysates (35ug/lane). SPR (arrow) was detected using the purified Pab.

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