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CFP Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB2748
产品名称
CFP Rabbit Polyclonal Antibody (Center)
别名
Properdin, Complement factor P, CFP, PFC
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001138724.1;NP_002612.1
Human Swissprot No.
P27918
特异性
This CFP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-223 amino acids from the Central region of human CFP.
稀释度
WB~~1:500
预测分子量
51kDa
同种型
Rabbit Ig
背景介绍
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
细胞定位
Secreted
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-CFP Antibody (Center) at 1:500 dilution + THP-1 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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