产品名称
AGT2 Rabbit Polyclonal Antibody
蛋白名称
Alanine--glyoxylate aminotransferase 2, mitochondrial (AGT 2) (EC 2.6.1.44) ((R)-3-amino-2-methylpropionate--pyruvate transaminase) (EC 2.6.1.40) (Beta-ALAAT II) (Beta-alanine-pyruvate aminotransferase) (D-AIBAT)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9BYV1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BYV1/entry
Mouse Swissprot No.
Q3UEG6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UEG6
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q64565
免疫原
Synthesized peptide derived from human protein . at AA range: 340-420
特异性
AGT2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
信号通路
Alanine; aspartate and glutamate metabolism;Glycine; serine and threonine metabolism;
功能
catalytic activity:(R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.,catalytic activity:L-alanine + glyoxylate = pyruvate + glycine.,cofactor:Pyridoxal phosphate.,similarity:Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homotetramer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
