BD-PB2724-SGMS2 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

SGMS2 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2724

产品名称

SGMS2 Rabbit Polyclonal Antibody (C-term)

别名

Phosphatidylcholine:ceramide cholinephosphotransferase 2, Sphingomyelin synthase 2, SGMS2, SMS2

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_001129729.1;NP_001129730.1;NP_689834.1

Human Swissprot No.

Q8NHU3

特异性

This SGMS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 338-365 amino acids from the C-terminal region of human SGMS2.

稀释度

WB~~1:1000

预测分子量

42kDa

同种型

Rabbit Ig

背景介绍

Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. SGMS2 is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. This protein is required for cell growth.

组织表达

Brain, heart, kidney, liver, muscle and stomach. Also expressed in a number of cell lines such as carcinoma HeLa cells, hepatoma Hep-G2 cells, and colon carcinoma Caco-2 cells

细胞定位

Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Primarily localized at the plasma membrane with a small fraction at the Golgi apparatus.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of SGMS2 Antibody (C-term) in HepG2 cell line lysates (35ug/lane). SGMS2 (arrow) was detected using the purified Pab.

Western blot analysis of SGMS2 Antibody (C-term) in mouse spleen tissue lysates (35ug/lane). SGMS2 (arrow) was detected using the purified Pab.

Western blot analysis of SGMS2 (arrow) using rabbit polyclonal SGMS2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SGMS2 gene.