产品名称
TBCE Rabbit Polyclonal Antibody (Center)
别名
Tubulin-specific chaperone E, Tubulin-folding cofactor E, TBCE
Human Gene ID
NP_001072983.1;NP_003184.1
Human Swissprot No.
Q15813
特异性
This TBCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-392 amino acids from the Central region of human TBCE.
背景介绍
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
