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SPN Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB2709
产品名称
SPN Rabbit Polyclonal Antibody (Center)
别名
Leukosialin, Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, CD43, SPN, CD43
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001025459.1;NP_003114.1
Human Swissprot No.
P16150
特异性
This SPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the Central region of human SPN.
稀释度
WB~~1:8000
预测分子量
40kDa
同种型
Rabbit Ig
背景介绍
Sialophorin (leukosialin) is a major sialoglycoprotein on the surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes, which appears to be important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation.
组织表达
Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas
细胞定位
Membrane; Single-pass type I membrane protein. Cell projection, microvillus {ECO:0000250|UniProtKB:P13838}. Cell projection, uropodium {ECO:0000250|UniProtKB:P15702}. Note=Localizes to the uropodium and microvilli via its interaction with ERM proteins (EZR, RDX and MSN) {ECO:0000250|UniProtKB:P13838, ECO:0000250|UniProtKB:P15702}
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

All lanes : Anti-SPN Antibody (Center) at 1:8000 dilution Lane 1: Jurkat whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 40 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

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