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FANCC Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB2700
产品名称
FANCC Rabbit Polyclonal Antibody (C-term)
别名
Fanconi anemia group C protein, Protein FACC, FANCC, FAC, FACC
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_000127.2;NP_001230672.1
Human Swissprot No.
Q00597
特异性
This FANCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-555 amino acids from the C-terminal region of human FANCC.
稀释度
WB~~1:1000;IF~~1:25
预测分子量
63kDa
同种型
Rabbit Ig
背景介绍
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This protein is for complementation group C.
组织表达
Ubiquitous.
细胞定位
Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of lysates from HepG2,HL-60 cell line (from left to right),using FANCC Antibody (C-term)at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.

Immunofluorescent analysis of U251 cells, using FANCC Antibody (C-term). BD-PB2700 was diluted at 1:25 dilution. Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). DAPI was used to stain the cell nuclear (blue).

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