产品名称
ARF5 Rabbit Polyclonal Antibody
蛋白名称
ADP-ribosylation factor 5
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P84085
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P84085/entry
Mouse Swissprot No.
P84084
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P84084
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P84083
免疫原
Synthesized peptide derived from human protein . at AA range: 40-120
特异性
ARF5 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
ADP ribosylation factor 5(ARF5) Homo sapiens This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010],
组织表达
Brain,Lung,Skin,Tongue,
细胞定位
Golgi apparatus . Cytoplasm, perinuclear region . Membrane ; Lipid-anchor . Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor .
功能
function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.,similarity:Belongs to the small GTPase superfamily.,similarity:Belongs to the small GTPase superfamily. Arf family.,subunit:Binds ASAP2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
