BD-PB2665-CLDN18 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

CLDN18 Rabbit Polyclonal Antibody (C-term)

产品详情相关文献产品问答相关产品

产品基本信息

产品货号

BD-PB2665

产品名称

CLDN18 Rabbit Polyclonal Antibody (C-term)

别名

Claudin-18, CLDN18

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001002026.1;NP_057453.1

Human Swissprot No.

P56856

特异性

This CLDN18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-259 amino acids from the C-terminal region of human CLDN18.

稀释度

WB~~1:2000

预测分子量

28kDa

同种型

Rabbit Ig

背景介绍

CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells.

组织表达

Isoform A1: Expression is restricted to the lung (PubMed:19047087). Isoform A2: Expression is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level) (PubMed:19047087)

细胞定位

Cell junction, tight junction {ECO:0000250|UniProtKB:P56857}. Cell membrane {ECO:0000250|UniProtKB:P56857}; Multi-pass membrane protein. Note=Localizes to tight junctions in epithelial cells {ECO:0000250|UniProtKB:P56857}

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Anti-CLDN18 Antibody (C-term) at 1:2000 dilution + Human lung tissue lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.