BD-PB2649-SPRR1B Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

SPRR1B Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2649

产品名称

SPRR1B Rabbit Polyclonal Antibody (C-term)

别名

Cornifin-B, 149 kDa pancornulin, Small proline-rich protein IB, SPR-IB, SPRR1B

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_003116.2

Human Swissprot No.

P22528

特异性

This SPRR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-89 amino acids from the C-terminal region of human SPRR1B.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

10kDa

同种型

Rabbit Ig

背景介绍

SPRR1B is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.

组织表达

Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea

细胞定位

Cytoplasm.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of SPRR1B Antibody (C-term) in MDA-MB231, MDA-MB435 cell line lysates (35ug/lane). SPRR1B (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with SPRR1B Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.