产品名称
HIST3H3 Rabbit Polyclonal Antibody (N-term)
别名
Histone H31t, H3/t, H3t, H3/g, HIST3H3, H3FT
Human Gene ID
NP_003484.1
Human Swissprot No.
Q16695
特异性
This HIST3H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST3H3.
背景介绍
HIST3H3 is are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.
组织表达
Expressed in testicular cells.
细胞定位
Nucleus. Chromosome.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
