BD-PB2617-JAKMIP1 Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

JAKMIP1 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB2617

产品名称

JAKMIP1 Rabbit Polyclonal Antibody (Center)

别名

Janus kinase and microtubule-interacting protein 1, GABA-B receptor-binding protein, Multiple alpha-helices and RNA-linker protein 1, Marlin-1, JAKMIP1, GABABRBP, JAMIP1, MARLIN1

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001092903.1;NP_653321.1

Human Swissprot No.

Q96N16

特异性

This JAKMIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human JAKMIP1.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

73kDa

同种型

Rabbit Ig

背景介绍

JAKMIP1 associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. It may play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.

组织表达

Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine

细胞定位

Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Colocalizes with the microtubule network Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of JAKMIP1 Antibody (Center) in 293 cell line lysates (35ug/lane). JAKMIP1 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human brain tissue reacted with JAKMIP1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.