产品名称
GSDMB Rabbit Polyclonal Antibody (Center)
别名
Gasdermin-B, Gasdermin-like protein, GSDMB, GSDML
Human Gene ID
NP_001035936.1;NP_001159430.1;NP_001159431.1;NP_061000.2
Human Swissprot No.
Q8TAX9
特异性
This GSDMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human GSDMB.
背景介绍
GSDMB is a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.
组织表达
In the gastrointestinal tract, expressed in proliferating cells, including in the basal cell layer of esophagus and in isthmus/neck of stomach.
细胞定位
[Gasdermin-B]: Cytoplasm. Note=Vesicular localization in the apical region of gastric chief cells and colonic surface mucous cells, and the basal region of neuroendocrine cells
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
