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ACTR3B Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB2597
产品名称
ACTR3B Rabbit Polyclonal Antibody (C-term)
别名
Actin-related protein 3B, ARP3-beta, Actin-like protein 3B, Actin-related protein ARP4, ACTR3B, ARP11, ARP4
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Gene ID
NP_001035225.1;NP_065178.1
Human Swissprot No.
Q9P1U1
特异性
This ACTR3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-352 amino acids from the C-terminal region of human ACTR3B.
稀释度
WB~~1:1000
预测分子量
48kDa
同种型
Rabbit Ig
背景介绍
ACTR3B plays a role in the organization of the actin cytoskeleton. It may function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks and may decrease the metastatic potential of tumors.
组织表达
Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential
细胞定位
Cytoplasm, cytoskeleton. Cell projection
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Western blot analysis of ACTR3B Antibody (C-term) in K562, CEM, HL-60 cell line lysates (35ug/lane). ACTR3B (arrow) was detected using the purified Pab.

Western blot analysis of ACTR3B Antibody (C-term) in mouse bladder tissue lysates (35ug/lane). ACTR3B (arrow) was detected using the purified Pab.

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