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PPM1G Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB2589
产品名称
PPM1G Rabbit Polyclonal Antibody (Center)
别名
Protein phosphatase 1G, Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, PP2C-gamma, Protein phosphatase magnesium-dependent 1 gamma, PPM1G, PPM1C
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Gene ID
NP_817092.1
Human Swissprot No.
O15355
特异性
This PPM1G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-180 amino acids from the Central region of human PPM1G.
稀释度
WB~~1:1000
预测分子量
59kDa
同种型
Rabbit Ig
背景介绍
PPM1G is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
组织表达
Widely expressed. Most abundant in testis, skeletal muscle, and heart
细胞定位
Cytoplasm. Membrane; Lipid-anchor
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Western blot analysis of hPPM1G-C164 in 293 cell line lysates (35ug/lane). PPM1G (arrow) was detected using the purified Pab.

Western blot analysis of hPPM1G-C164 in mouse heart tissue lysates (35ug/lane). PPM1G (arrow) was detected using the purified Pab.

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