产品名称
NEK11L Rabbit Polyclonal Antibody (C-term)
别名
Serine/threonine-protein kinase Nek11, Never in mitosis A-related kinase 11, NimA-related protein kinase 11, NEK11 (
HGNC:18593)
Human Gene ID
NP_001139475.1;NP_079076.3;NP_665917.1
Human Swissprot No.
Q8NG66
特异性
This NEK11L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-510 amino acids from the C-terminal region of human NEK11L.
背景介绍
NEK11 belongs to the NIMA family of kinases, which are involved in DNA replication and genotoxic stress responses (Noguchi et al., 2002 [PubMed 12154088]).[supplied by OMIM]
组织表达
Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
细胞定位
Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase (PubMed:12154088). Accumulates in the nucleolus in G1/S-arrested cells (PubMed:15161910).
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
