BD-PB2542-PRKCDBP Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

PRKCDBP Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB2542

产品名称

PRKCDBP Rabbit Polyclonal Antibody (Center)

别名

Protein kinase C delta-binding protein, Cavin-3, Serum deprivation response factor-related gene product that binds to C-kinase, hSRBC, PRKCDBP, SRBC

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_659477.2

Human Swissprot No.

Q969G5

特异性

This PRKCDBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-144 amino acids from the Central region of human PRKCDBP.

稀释度

WB~~1:1000

预测分子量

28kDa

同种型

Rabbit Ig

背景介绍

PRKCDBP was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this protein in cultured cell lines is strongly induced by serum starvation, and was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein.

组织表达

Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level). Strongly expressed in mammary and epithelial cells.

细胞定位

Cytoplasm {ECO:0000250|UniProtKB:Q91VJ2}. Membrane, caveola. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q91VJ2}. Note=Localizes in the caveolae in a caveolin-dependent manner.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Western blot analysis of anti-PRKCDBP Antibody (Center) in A2058 cell line lysates (35ug/lane). PRKCDBP (arrow) was detected using the purified Pab.

Western blot analysis of PRKCDBP (arrow) using rabbit polyclonal PRKCDBP Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRKCDBP gene (Lane 2) .