BD-PB2541

BICD2 Rabbit Polyclonal Antibody (C-term)

Protein bicaudal D homolog 2, Bic-D 2, BICD2, KIAA0699

常规抗体

WB

Human

NP_001003800.1;NP_056065.1

Q8TD16

This BICD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 787-818 amino acids from the C-terminal region of human BICD2.

WB~~1:1000;IHC-P~~1:100~500

94kDa

Rabbit Ig

BICD2 is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8.

Ubiquitous.

Golgi apparatus. Cytoplasm, cytoskeleton. Cytoplasm. Nucleus envelope. Nucleus, nuclear pore complex. Note=In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Localizes to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae in a RANBP2-dependent manner during G2 phase of the cell cycle (PubMed:20386726). {ECO:0000250|UniProtKB:Q921C5, ECO:0000269|PubMed:11864968, ECO:0000269|PubMed:20386726}

现货

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.