BD-PB2535-TYRO3 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

TYRO3 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB2535

产品名称

TYRO3 Rabbit Polyclonal Antibody (C-term)

别名

Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase BYK, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase TIF, TYRO3, BYK, DTK, RSE, SKY, TIF

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_006284.2

Human Swissprot No.

Q06418

特异性

This TYRO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 842-873 amino acids from the C-terminal region of human TYRO3.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

97kDa

同种型

Rabbit Ig

背景介绍

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

组织表达

Abundant in the brain and lower levels in other tissues

细胞定位

Cell membrane; Single-pass type I membrane protein

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Western blot analysis of anti-SKY Pab in mouse brain lysate. SKY (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Western blot analysis of SKY (arrow) using rabbit polyclonal SKY Antibody (C-term).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SKY gene (Lane 2) .

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.