BD-PB2522

BBS4 Rabbit Polyclonal Antibody (Center)

Bardet-Biedl syndrome 4 protein, BBS4

常规抗体

WB

Human

NP_001239607.1;NP_149017.2

Q96RK4

This BBS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-369 amino acids from the Central region of human BBS4.

WB~~1:1000

58kDa

Rabbit Ig

BBS4 contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyglucosamine transferase. Mutations in the gene encoding this protein have been observed in patients with Bardet-Biedl syndrome type 4. BBS4 may play a role in pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation.

Ubiquitously expressed. The highest level of expression is found in the kidney

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q8C1Z7}. Cell projection, cilium {ECO:0000250|UniProtKB:Q8C1Z7}. Note=Localizes to the pericentriolar material. Centrosomal localization requires dynein (By similarity) Localizes to the connecting cilium of photoreceptor cells (By similarity). {ECO:0000250|UniProtKB:Q8C1Z7}

现货

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.