BD-PB2516

EHD3 Rabbit Polyclonal Antibody (Center)

EH domain-containing protein 3, PAST homolog 3, EHD3, EHD2, PAST3

常规抗体

WB

Human

NP_055415.1

Q9NZN3

This EHD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-216 amino acids from the Central region of human EHD3.

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

61kDa

Rabbit Ig

EHD3 plays a role in endocytic transport.

Highly expressed in heart and brain and moderately expressed in kidney, liver, and placenta

Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the ciliary pocket from where the cilium protrudes (PubMed:25686250) Colocalizes with RAB8A and MYO5B to a cytoplasmic tubular network devoid of RAB11A (By similarity). Colocalizes with ANK2 in myocyte perinuclear region (PubMed:20489164). Colocalizes with BACE1 in tubulovesicular cytoplasmic membranes. Colocalizes with BACE1 and APP amyloid beta proteins in hippocampal mossy fiber terminals (By similarity). {ECO:0000250|UniProtKB:Q9QXY6, ECO:0000269|PubMed:20489164, ECO:0000269|PubMed:25686250}

现货

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.